Saturday January 23, 2010


Q: Can you use diuretics in DI (Diabetes Insipidus)?

Answer: yes - you can use Hydrochlorothiazide.

Thiazide diuretic decreases urinary volume in absence of ADH. It may induce mild volume depletion and cause proximal salt and water retention, thereby reducing flow to the ADH-sensitive distal nephron. Effects are additive to other agents.