Wednesday January 13, 2010


Q: Which of the following drugs has strong anti-emetic property?

A) Heparin
B) Digoxin
C) Cefepime
D) Haldol (Haloperidol)
E) Zantac (Ranitidine)



Answer: D

The peripheral antidopaminergic effects of haloperidol account for its strong antiemetic activity. There, it acts at the chemoreceptor trigger zone (CTZ). Haloperidol is useful to treat severe forms of nausea/emesis such as those resulting from chemotherapy. The peripheral effects lead also to a relaxation of the gastric sphincter muscle.

None of the other drugs has anti-emetic property.